(B) A549 cells were synchronized in S-phase and treated with 10 M ATM and/or ATR inhibitors (Ku55933 and Nu6027) for 1 hour prior to CPT treatment (10 M for 2.5 hrs.) Whole cell lysates were subjected to DNase I digestion and 5% of the sample was loaded as input. respectively. Neither the phosphorylation of RPA… Continue reading (B) A549 cells were synchronized in S-phase and treated with 10 M ATM and/or ATR inhibitors (Ku55933 and Nu6027) for 1 hour prior to CPT treatment (10 M for 2