N. cytokines most associated with nonhealing forms of leishmaniasis are interleukin 4 (IL-4) and IL-10. For example, infection in BALB/c mice results in nonhealing disease associated with high levels of IL-4, and neutralizing IL-4 can promote resistance (21). IL-10 also contributes to susceptibility in BALB/c mice and also modulates protective immune responses in B6 mice… Continue reading N